Vit D

Review Article Indian J Med Res 127, jar against 2008, pp 229-238 preponderance & potential significance of vitamin D deficiency in Asian Indians R. Goswami, S.K. Mishra & N. Kochupillai Department of Endocrinology & Metabolism, All India Institute of Medical Sciences reinvigorated Delhi, India accredited October 5, 2007 Studies from our center and new(prenominal)wise parts of India have bony anxiety towards wide prevalence of vitamin D deficiency (VDD) in our country. VDD has been account in all age groups including toddlers, school children, large(predicate) women and their neonates and self-aggrandising males and females residing in rural and urban India. We reviewed implications of VDD in our universe ground on the preliminary data available from Indian studies on skeletal health. Besides, a brief review is do on the importance of VDD in various other disorders long-familiar in equivalent proportions among Indians such(prenominal) as showcase 2 diab etes mellitus (DM), cardiovascular diseases (CVD), immune competence including relation to tuberculosis, malignancy and osteoarthritis. Data from the occidental hemisphere have also associated VDD with increased prevalence of type 2DM, CVD, autoimmune disorders, tuberculosis, prostate, breast and colon malignancy and osteoarthritis. Such linkup has non been studied to assignment in our country.

Overall results of various studies conducted to age in urban and rural Indians indicate that widely everyday VDD is functionally relevant to skeletal health including osteomalacia and rickets. However, there is a need to explore its association with osteoporosis re! lated fractures and various other non skeletal disorders linked with VDD. Key words Osteomalacia - skeletal health - type 2 diabetes mellitus - vitamin D deficiency Overview Vitamin D is a secosteroid which is reborn into its active form via 1 ?-hydroxylase enzyme. Though kidney is the clear state of affairs for 1 ?-hydroxylase activity, it is also expressed in other tissues such as endothelial and vascular motionless muscle cells1....If you indirect request to get a abundant essay, order it on our website: BestEssayCheap.com

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